TARGETED STUDIES
Bladder Cancer
Journal of Agricultural and Food Chemistry 2010
The authors use biochemical extractions of Ganoderma spores to show that a polysaccharide fraction (LZP-F3) has cytotoxic effects on human bladder cells. The polysaccharide caused cell division arrest, by inducing a protein called P38.
Huang CY et al.
Jounal of Ethnopharmacology 2008
Interesting paper showing that anti-oxidants in Ganoderma spores had protective effect on bladder cell DNA exposed to carcinogenic compounds. One way the spores would help to prevent cancer or to treat it could be as a source of specific and powerful anti-oxidants.
Yuen JW et al.
Nutrion & Cancer 2008
Study linking Ganoderma extracts to anti-oxidant and telomerase-inhibition/apoptosis . By inhibiting telomerase, which affects the critical parts of the chromosome ends, the spores seem to trigger apoptosis in cell death in human bladder cancer cells.
Yuen JW et al.
Cancer Letters 2004
Experiments reveal that preparations of Ganoderma spores can inhibit the growth of human bladder cells. By studying the effects of the preparations on actin proteins, the scientists showed that Ganderma causes the proteins to polymerize excessively, leading to a blockage in the cell division.
Qing-Yi Lul
